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KMID : 0364020120450010060
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Korean Journal of Thoracic and Cardiovascular Surgery
2012 Volume.45 No. 1 p.60 ~ p.64
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Large Cell Neuroendocrine Carcinoma of the Thymus: A Two-Case Report
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Yoon Yong-Han
Kim Jae-Ho
Kim Kwang-Ho
Baek Wan-Ki
Lee Hyun-Kyu
Lee Moon-Hee
Lee Kyung-Hee
Kim Lucia
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Abstract
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A large cell neuroendocrine carcinoma (LCNEC) of the thymus is a very rare malignant tumor that has a very poor prognosis. The detailed clinical features of LCNEC are still unknown, including the long term prognoses and the definitive modalities of the treatment for LCNEC of the thymus. We are reporting 2 cases of an enlarged LCNEC of the thymus, both of which were diagnosed and treated by surgical resection followed by postoperative adjuvant chemoradiation therapy. Although recurrences and metastases of the LCNEC were noticed 1 and 4 years postoperatively for each case, aggressive surgical resection and adjuvant chemoradiation therapy may be helpful for a patient’s long term survival.
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KEYWORD
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Tumor, malignant, Thymus, Large cell neuroendocrine carcinoma, Surgery
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